Cart
sales@molnova.com
trans-isrib A17
CAS No. 1628478-15-8
trans-isrib A17( —— )
Catalog No. M35981 CAS No. 1628478-15-8
trans-isrib A17 (ISR-IN-1) is an potent inhibitor of the integrated stress response with EC50 of 0.6 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 55 | Get Quote |
|
| 5MG | 84 | Get Quote |
|
| 10MG | 126 | Get Quote |
|
| 25MG | 247 | Get Quote |
|
| 50MG | 363 | Get Quote |
|
| 100MG | 507 | Get Quote |
|
| 200MG | 687 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product Nametrans-isrib A17
-
NoteResearch use only, not for human use.
-
Brief Descriptiontrans-isrib A17 (ISR-IN-1) is an potent inhibitor of the integrated stress response with EC50 of 0.6 nM.
-
DescriptionISR-IN-1 (Compound 48) is an inhibitor of the integrated stress response (EC50: 0.6 nM).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1628478-15-8
-
Formula Weight487.32
-
Molecular FormulaC22H22Cl2F2N2O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 12.5 mg/mL (25.65 mM; Ultrasonic )
-
SMILESO(CC(N[C@H]1CC[C@H](NC(COC2=CC(F)=C(Cl)C=C2)=O)CC1)=O)C3=CC(F)=C(Cl)C=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11(8):870-80. ?
molnova catalog
related products
-
Debilon
Debilon shows cytotoxic activity against P-388 cells.
-
Acutumine
(?)-Acutumine is a tetracyclic chloroalkaloid that exhibits selective cytotoxicity to cultured human T cells and memory-enhancing properties in the Wistar rat model.
-
Chiniofon
Chiniofon, a halogenated 8-hydroxyquinoline, is used as an antiamebic drug. This type of anti-amebic drug exerts an anti-amebic effect by inhibiting intestinal commensal bacteria and affects amoebic dysentery, but has no effect on extra-intestinal amoebic parasites.
